Posts filed under Risk (126)

July 29, 2014

A treatment for unsubstantiated claims

A couple of months ago, I wrote about a One News story on ‘drinkable sunscreen’.

In New Zealand, it’s very easy to make complaints about ads that violate advertising standards, for example by making unsubstantiated therapeutic claims. Mark Hanna submitted a complaint about the NZ website of the company  selling the stuff.

The decision has been released: the complaint was upheld. Mark gives more description on his blog.

In many countries there is no feasible way for individuals to have this sort of impact. In the USA, for example, it’s almost impossible to do anything about misleading or unsubstantiated health claims, to the extent that summoning a celebrity to be humiliated publicly by a Senate panel may be the best option.

It can at least produce great television: John Oliver’s summary of the Dr Oz event is viciously hilarious

July 27, 2014

Air flight crash risk

David Spiegelhalter, Professor of the Public Understanding of Risk at Cambridge University, has looked at the chance of getting three fatal plane crashes in the same 8-day period, based on the average rate of fatal crashes over the past ten years.  He finds that if you look at all 8-day periods in ten years, three crashes is actually the most likely way for the worst week to turn out.

He does this with maths. It’s easier to do it by computer simulation: arrange the 91 crashes randomly among the 3650 days and count up the worst week. When I do this 10,000 times (which takes seconds). I get

crashes

 

The recent crashes were separate tragedies with independent causes — two different types of accident and one deliberate shooting — they aren’t related like, say, the fires in the first Boeing Dreamliners were. There’s no reason for the recent events should make you more worried about flying.

July 23, 2014

Average and variation

Two graphs from the NZ influenza surveillance weekly update (PDF, via Mark Hanna)

flu-averageflu-varying

Both show that the seasonal epidemic has started.  I think the second graph is more helpful in comparing this year to the past; showing the actual history for a range of years, rather than an average.  This sort of graph could handle a larger number of past years if they were all or mostly in, eg, thin grey lines, perhaps with this year, last year, and the worst recent year in colour.

The other news in the surveillance update is that the flu viruses that have been examined have overwhelming been H1N1 or H3N2, and both these groups are covered in this year’s vaccine.

The self-surveillance world

See anyone you know? (click to embiggen)

cats

 

This is a screenshot from I know where your cat lives, a project at Florida State University that is intended to illustrate the amount of detailed information available from location-tagged online photographs, without being too creepy — just creepy enough.

(via Robert Kosara and Keith Ng)

July 1, 2014

Facebook recap

The discussion over the Facebook experiment seems to involve a lot of people being honestly surprised that other people feel differently.

One interesting correlation based on my Twitter feed is that scientists involved in human subjects research were disturbed by the research and those not involved in human subjects research were not. This suggests our indoctrination in research ethics has some impact, but doesn’t answer the question of who is right.

Some links that cover most of the issues

June 29, 2014

Not yet news

When you read “The university did not reveal how the study was carried out” in a news story about a research article, you’d expect the story to be covering some sort of scandal. Not this time.

The Herald story  is about broccoli and asthma

They say eating up to two cups of lightly steamed broccoli a day can help clear the airways, prevent deterioration in the condition and even reduce or reverse lung damage.

Other vegetables with the same effect include kale, cabbage, brussels sprouts, cauliflower and bok choy.

Using broccoli to treat asthma may also help for people who don’t respond to traditional treatment.

‘How the study was carried out’ isn’t just a matter of detail: if they just gave people broccoli, they wouldn’t know what other vegetables had the same effect, so maybe it wasn’t broccoli but some sort of extract? Was it even experimental or just observational? And did they actually test people who don’t respond to traditional treatment? And what exactly does that mean — failing to respond is pretty rare, though failing to get good control of asthma attacks isn’t.

The Daily Mail story was actually more informative (and that’s not a sentence I like to find myself writing). They reported a claim that wasn’t in the press release

The finding due to sulforaphane naturally occurring in broccoli and other cruciferous vegetables, which may help protect against respiratory inflammation that can cause asthma.

Even then, it isn’t clear whether the research really found that sulforaphane was responsible, or whether that’s just their theory about why broccoli is effective. 

My guess is that the point of the press release is the last sentence

Ms Mazarakis will be presenting the research findings at the 2014 Undergraduate Research Conference about Food Safety in Shanghai, China.

That’s a reasonable basis for a press release, and potentially for a story if you’re in Melbourne. The rest isn’t. It’s not science until they tell you what they did.

Ask first

Via The Atlantic, there’s a new paper in PNAS (open access) that I’m sure is going to be a widely cited example by people teaching research ethics, and not in a good way:

 In an experiment with people who use Facebook, we test whether emotional contagion occurs outside of in-person interaction between individuals by reducing the amount of emotional content in the News Feed. When positive expressions were reduced, people produced fewer positive posts and more negative posts; when negative expressions were reduced, the opposite pattern occurred. These results indicate that emotions expressed by others on Facebook influence our own emotions, constituting experimental evidence for massive-scale contagion via social networks.

More than 650,000 people had their Facebook feeds meddled with in this way, and as that paragraph from the abstract makes clear, it made a difference.

The problem is consent.  There is a clear ethical principle that experiments on humans require consent, except in a few specific situations, and that the consent has to be specific and informed. It’s not that uncommon in psychological experiments for some details of the experiment to be kept hidden to avoid bias, but participants still should be given a clear idea of possible risks and benefits and a general idea of what’s going on. Even in medical research, where clinical trials are comparing two real treatments for which the best choice isn’t known, there are very few exceptions to consent (I’ve written about some of them elsewhere).

The need for consent is especially clear in cases where the research is expected to cause harm. In this example, the Facebook researchers expected in advance that their intervention would have real effects on people’s emotions; that it would do actual harm, even if the harm was (hopefully) minor and transient.

Facebook had its research reviewed by an Institutional Review Board (the US equivalent of our Ethics Committees), and the terms of service say they can use your data for research purposes, so they are probably within the law.  The psychologist who edited the study for PNAS said

“I was concerned,” Fiske told The Atlantic, “until I queried the authors and they said their local institutional review board had approved it—and apparently on the grounds that Facebook apparently manipulates people’s News Feeds all the time.”

Fiske added that she didn’t want the “the originality of the research” to be lost, but called the experiment “an open ethical question.”

To me, the only open ethical question is whether people believed their agreement to the Facebook Terms of Service allowed this sort of thing. This could be settled empirically, by a suitably-designed survey. I’m betting the answer is “No.” Or, quite likely, “Hell, no!”.

[Update: Story in the Herald]

May 30, 2014

Levels of evidence

If you find that changing your diet in some way makes you feel happier and healthier, that’s a good thing.  It doesn’t matter whether the same change would be useful for most people, or only useful for you. It doesn’t matter whether the change is a placebo effect. It doesn’t even matter if it’s an illusion, a combination of regression to the mean and confirmation bias. You might check with a doctor or dietician as to whether the change is dangerous, but otherwise, go for it.

If you want to campaign for the entire community to make a change in their diet, you need to have evidence that it’s better on average for the entire community. A few people’s subjective experience isn’t good enough.  Good quality observational data might be all you can manage if the benefits are subtle or take years to appear, but if you’re claiming dramatic short-term benefits you should be able to demonstrate them in a randomised controlled trial.

The reason for mentioning this is that PETA has been making friends again. They’re trying to link milk consumption to autism. They don’t even pretend to have any evidence that milk causes autism, and the evidence that milk-free diet has a beneficial effect in people with autism is very weak.  That is, there are a few studies that suggest a benefit, but the benefit is smaller in studies with more reliable designs, and absent in the best-designed studies.  The most recent review of the evidence concluded that dairy-free or gluten-free diets should only be tried for people who have some separate evidence of food intolerance.  After reading the review, I would agree.

There are respectable arguments against dairy farming, both ethical and environmental. Scaremongering about autism isn’t one of them.

May 23, 2014

Distrust the center

Automated location information can be very useful, but if the ‘location’ is an area and the automated result is a single point, it’s easy to get misled.

May 22, 2014

Big Data social context

From Cathy O’Neil: Ignore data, focus on power (and, well, most of the stuff on her blog)

From danah boyd and Kate Crawford: Critical Questions for Big Data

Will large-scale search data help us create better tools, services, and public goods? Or will it usher in a new wave of privacy incursions and invasive marketing? Will data ana- lytics help us understand online communities and political movements? Or will it be used to track protesters and suppress speech? Will it transform how we study human communication and culture, or narrow the palette of research options and alter what ‘research’ means?