October 22, 2015

The wine when it is red

Q: Are you going to have a glass of wine tonight?

A: You mean as a celebration?.

Q: No, because a glass of red wine has the same benefits as a gym session. The Herald story?

A: Yeah, nah.

Q: What part of “Red wine equal to a gym workout – study” don’t you understand?

A: How they got that from the research.

Q: Was this just correlations again?

A: No, it was a real experimental study.

Q: So I’m guessing you’re going to say “in mice”?

A: Effectively. It was in rats.

Q: They gave some rats red wine and made others do gym workouts?

A: No, there wasn’t any red wine.

Q: But the story… ah, I see. “A compound found in red wine”. They gave the rats this compound directly?

A: That’s right

Q: And the gym workouts?

A: Basically, yes. The rats did treadmill runs, though they don’t report that they had headphones on at the time.

Q: So the resveratrol group ended up fitter than the exercise group?

A: No, both groups got the workouts. The resveratrol plus exercise group ended up fitter than the group just getting exercise.

Q: So, really, it’s about a glass of red wine plus a gym workout, not instead of a gym workout? If it was people, not rats?

A: Well, not “a glass”.

Q: How many glasses?

A: The rats got 146mg resveratrol per kg of weight per day. One standard conversion rate is to divide by 7 to get mg/kg in humans: about 20. So for a 60kg person, that’s about 1200mg/day of resveratrol.

Q: How much is in a glass of wine?

A: It depends on the size, but at 5 glasses per bottle, maybe 0.3 mg

Q: So we might need bigger glasses, then.

A: At least you’ll get plenty of exercise lifting them.

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Thomas Lumley (@tslumley) is Professor of Biostatistics at the University of Auckland. His research interests include semiparametric models, survey sampling, statistical computing, foundations of statistics, and whatever methodological problems his medical collaborators come up with. He also blogs at Biased and Inefficient See all posts by Thomas Lumley »

Comments

  • avatar

    Suggest you look at the drinking habits of the best 1% of T1 diabetics over 50 and >15 years disease duration, cw average T1.. Captive population and high risk so minimal sample size required.
    Or will you find something public health physiciansdon’t want you to find?
    One problem with doing this in NZ might be the apparently poor outcomes of older T1s and Addison’s patients in NZ. Do you have a law which prevents patients with good outcomes from posting on social media?

    8 years ago